FLUORESCENT PROBES FOR MAMMALIAN THIOREDOXIN REDUCTASE: MECHANISTIC ANALYSIS, CONSTRUCTION STRATEGIES, AND FUTURE PERSPECTIVES

Fluorescent Probes for Mammalian Thioredoxin Reductase: Mechanistic Analysis, Construction Strategies, and Future Perspectives

The modulation of numerous signaling pathways is orchestrated by redox regulation of cellular environments.Maintaining dynamic redox homeostasis is of utmost importance for human health, given the common occurrence of altered redox status in various pathological conditions.The cardinal component of the thioredoxin system, mammalian thioredoxin redu

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Feasibility assessment of an 8-week attention-based training programme in the management of chronic spontaneous urticaria

Abstract Background Chronic spontaneous urticaria is a common disorder that is poorly understood and frequently misdiagnosed.Psychological difficulties are a significant factor in dermatological diseases and may also aggravate symptom burden.Mind-body interventions are used as a complementary approach to alleviate symptoms in chronic diseases and m

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Effect of Friction Stir Welding Parameters on the Mechanical and Microstructure Properties of the Al-Cu Butt Joint

Friction Stir Welding (FSW) is a solid-state welding process used for welding similar and dissimilar materials.FSW is especially suitable to join sheet Al alloys, and this technique allows different material couples to be welded continuously.In this study, 1050 Al alloys and commercially pure Cu were produced at three different tool rotation speeds

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Immune responses during COVID-19 infection

Over the past 16 years, three coronaviruses (CoVs), severe acute respiratory syndrome CoV (SARS-CoV) in 2002, Middle East respiratory syndrome CoV (MERS-CoV) in 2012 and 2015, and SARS-CoV-2 in 2020, have been causing severe and fatal human epidemics.The unpredictability of coronavirus disease-19 (COVID-19) poses a Vehicle Hitch Locks major burden

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A Case of Ralstonia pickettii Bloodstream Infection and the Growing Problem of Healthcare Associated Infections in Frail Older Adults

Frailty is a clinically measurable state of vulnerability to developing increased dependency and/or mortality when Sleep exposed to a stressor.Chronic diseases, aggressive treatments, antibiotic overuse, microbiota changes, immune senescence, and increased use of medical devices and implants (i.e., central lines and catheters) expose modern patient

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